Best suffered his second concussion of the year in the second half of last week's loss to the San Francisco 49ers and did not practice all week. Maurice Morris is expected to start in Best's absence, with Keiland Williams and Stefan Logan as his backups.
The Lions also signed Eldra Buckley for depth at the position. Buckley practiced with the No. 1 punt team today.
"We’ll have Maurice Morris, and we’ll have Keiland and Eldra get moving quickly, and then, like you guys talked about yesterday, we still have Logan that can be a ball carrier for us," Lions coach Jim Schwartz said today. "We won’t run out of ball carriers in the game."
Receiver Rashied Davis (foot) and safety Vince Fuller (elbow) are doubtful and not expected to play Sunday, while cornerback Aaron Berry (groin) is questionable.
Coach Jim Schwartz said any details on Harrison's condition would have to come from the player. Harrison had surgery Friday after a brain tumor was discovered during a physical for a trade with the Philadelphia Eagles that was nullified because of the condition, the Detroit Free Press reported.
"I had a chance to visit with him this morning," Schwartz said. "He was in very good spirits, but after that, I don't know if I want to talk too much."
Schwartz said earlier this week that Best began experiencing "concussion-like symptoms" after last weekend's loss to San Francisco. Best also missed time during this preseason because of a concussion, and when he was a college player at California, he missed a few games after a fall knocked him out and sent him to the hospital with a concussion and sore back.
The Lions were sending Harrison to the Eagles in a trade that would have brought running back Ronnie Brown to Detroit. That deal was voided, and Harrison's health is now foremost on the team's mind.
"It puts a lot of things in perspective," Lions receiver Nate Burleson said.
Harrison's agent, Mitch Frankel, did not return phone and email messages. Bob Kubiak, who coached Harrison in high school in Kalamazoo, said his thoughts are with his former player.
"If anybody's going to beat whatever he's got, that would be this guy," Kubiak said.
The Lions signed running back Eldra Buckley while moving Harrison to the reserve list. Buckley played for Philadelphia the past two seasons.
Detroit linebacker Justin Durant, also recovering from a concussion, says he expects to play Sunday.
"I feel as good as I think I can feel right now," Durant said. "Hopefully I'm 100 (percent) and hopefully I'm OK."
Tight end Tony Scheffler and linebacker Justin Durant, both returning from concussions, are probable.
The NFL also confirmed that tight end Brandon Pettigrew was fined $7,500 for a chop-block penalty against the 49ers. San Francisco linebacker Aldon Smith was fined $15,000 for striking Lions quarterback Matthew Stafford below the knee on a roughing-the-passer penalty.
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